Emhlabeni wokuhle okushintsha ngokushesha, ukwelashwa kobuhle okungangenisi emzimbeni kusuka ekubeni yizivivinyo zokugcina kuye ekubeni yizinto ezilindelwe umphakathi wonkana, futhi zimbalwa izobuchwepheshe ezibonisa lolu shintsho ngendlela eqinisekisa njengoba kwenza idivayisi yobuhle ye-cold plasma. I-INKUE, umkhiqizi wochwepheshe onolwazi lweminyaka eminingi wezinto zobuhle ze-plasma osukela ngo-1992, imi phambili kulo mnyakazo ngokuletha imishini esezingeni lokuhweba egxile emtholampilo exhumanisa ukusebenza kwesaluni nokunethezeka kokusetshenziswa ekhaya. Njengoba abathengi beba nokungabaza okukhulayo ngezinqubo ezinamandla nezikhathi ezinde zokululama, i-plasma inikeza indlela ephakathi eqabula umoya eletha ukulungiswa okubonakalayo kwesikhumba ngaphandle kokulimaza ukuphepha noma ukunethezeka. Lesi sihloko sihloselwe ukuhlomisa ochwepheshe bobuhle, abasabalalisi, nabanikazi bemikhiqizo ngokuqonda okuphelele kobuchwepheshe be-cold plasma, isayensi eyisisekelo yako, kanye nezinzuzo eziyingqayizivele zokuncintisana ezilethwa yi-INKUE. Kusukela kufiziksi eyisisekelo ye-plasma kuya ezinqubweni zokusetshenziswa ezinemininingwane kanye nobufakazi bemtholampilo, sizohlola zonke izici ezibalulekile lapho ukhetha idivayisi yobuhle ye-plasma yebhizinisi lakho. Ekupheleni kwalesi siqondisi, ngeke nje uqonde ukuthi kungani i-cold plasma iyikusasa lokunakekelwa kwesikhumba kodwa futhi uzoqonda ukuthi kungani i-INKUE ihlala ingumlingani othembekile wezisombululo zobuhle ezithuthukile emhlabeni wonkana.

Ukuze uthakasele ngempela lokho okwenziwa yithuluzi lobuhle be-cold plasma, umuntu kufanele aqale aqonde imvelo evamile kodwa engavamile ye-plasma ngokwayo. Ngamazwi alula, i-plasma ihlukaniswa njengesimo sesine sezinto, sihlangene neziqinile, uketshezi, namagesi, futhi yenzeka lapho igesi imunca amandla anele okwenza ama-athomu ayo alahlekelwe ama-electron futhi abe yi-ionized. Lokhu kwenziwa kwe-ionization kukhiqiza ingxube yama-ion anegethivu, ama-electron amahhala, nezinhlayiya ezingathathi hlangothi ezisebenza kakhulu, ezihlangene zakha indawo yokuhamba kagesi eziphatha ngendlela ehluke kakhulu kunanoma iyiphi igesi evamile. Umlilo, umbani, kanye nama-aurora akhanyayo esibhakabhakeni sasemazingeni asenyakatho konke kuyizibonelo zemvelo ze-plasma, okubonisa amandla ayo amangalisayo okudlulisa amandla nokusebenzisana nezinto ezizungezile. Lapho lesi simo samandla sisetshenziswa ezingeni lokushisa eliphansi, umphumela uba yi-cold plasma, umfudlana olawulwayo wegesi eli-ionized elihlala lipholile ngokwanele ukuthinta isikhumba somuntu ngaphandle kokubangela ukusha noma ukulimala kokushisa. Lesi sakhiwo esiyingqayizivele sakha isisekelo saso kanye samathuluzi obuhle be-plasma besimanje, okuvumela abelaphi ukuthi bahambise imiphumela enamandla yezinto eziphilayo kuyilapho bebeka phambili ukunethezeka nokuphepha kwesiguli kuzo zonke izinyathelo.

I-plasma ebandayo iyamangalisa kakhulu ngoba igxilisa inani elikhulu lamandla kagesi namakhemikhali endaweni encane egxilile kuyilapho igcina izinga lokushisa elingaphezulu elizwakala kahle esikhunjeni. Ososayensi bathole ukuthi lapho i-plasma ithinta izicubu eziphilayo, iqala uchungechunge lwezimpendulo zebhayoloji ezisukela ekuncishisweni kwamagciwane kuya ekwandiseni umzimba wamaseli nasekusheshiseni ukuphola kwamanxeba. Ngenxa yokuthi igesi ngokwayo ingashintshwa ngokulungisa i-voltage, imvamisa, nokwakheka kwengxube yegesi, abacwaningi nonjiniyela bangaklama amadivayisi anezinhlobo zokwelapha ezihluke kakhulu. Lokhu kuguquguquka yikona okwenza i-INKUE ikwazi ukunikeza amathuluzi obungcweti abhekana namagcunsula, ukushintsha kombala, imibimbi, nokuxega kwesikhumba ngeplatifomu eyodwa. Njengoba sihlola lobu buchwepheshe kabanzi, kuyacaca ukuthi i-plasma ebandayo ayiyona nje into entsha kodwa iyindlela yokwelapha ecwaningwa ngokunzulu enezimpande ezijulile kufiziksi, ibhayoloji, nesayensi yezifo zesikhumba.

Idivayisi yobuhle be-plasma ebandayo iyithuluzi le-elekthronikhi elithuthukisiwe elikhiqiza ukukhishwa kwe-plasma ezingeni lokushisa eliphansi esihlokweni se-handpiece futhi liyilethe esikhumbeni ngezinjongo zokwelapha nezobuhle. Esikhundleni sokuncika ekushiseni, ekuqothuleni, noma ezinalitini ezingenayo, lawa madivayisi asebenzisa amakhemikhali asebenzayo egesi eline-ionized ukuze avuse izindlela zemvelo zokulungisa isikhumba futhi akhuthaze ukuvuselelwa kwesikhathi eside. Ithimba lobunjiniyela le-INKUE linikele iminyaka ekuthuthukiseni indlela ye-dielectric barrier discharge (DBD), indlela eyinkimbinkimbi ekhiqiza indawo ye-plasma efanayo, ezinzile enokulawula okukhethekile nokuphindaphindeka. Indlela ye-DBD ihilela ukubeka isendlalelo se-dielectric insulating phakathi kwama-electrode, okuvimbela ukugeleza kwamandla amaningi futhi kugcine ukukhishwa kusakazekile futhi kuphephile ezicutshini zebhayoloji. Lokhu kubangela ukwelashwa okuzwakala kuthambile kwi-epidermis ngenkathi kukhiqiza ingxube ecebile yezinhlobo ezisebenzayo ezijulile ezingqimbeni zesikhumba, okuxhumanisa ngempumelelo umehluko phakathi kokusebenza okuphezulu nokungakhululeki okuncane.

Isimiso esiyisisekelo esingemuva kwale mishini silula ngendlela enhle: i-plasma yezinga lokushisa eliphansi iqala ukusabela okulawulwayo okufana nokuvuvukala okuvula ama-fibroblast, kukhuthaze ukuhlelwa kabusha kwe-collagen, futhi kusheshise ukushintshwa kwamaseli, konke ngaphandle kokulimala kokushisa okuhambisana nokwelashwa kwendabuko kokuchitha. Lapho i-plasma ithinta ungqimba lwangaphandle lwesikhumba, iletha isignali yesikhashana kagesi neyamakhemikhali etholwa amaseli esikhumba njengomkhombandlela wokuqala izinqubo zokulungisa nokuvuselela. Ezinsukwini nasemavikini alandelayo, iziguli ziqaphela ukuthuthuka okuqhubekayo kokuthungwa, ithoni, ukuqina, nokukhanya okuphelele njengoba izendlalelo ezijulile ze-dermis zisabela kulesi sikhuthazo. Imishini ye-INKUE yakhelwe ukuletha le nzuzo ngokuthembekile kuzo zonke izinhlobo zesikhumba, ngokunaka ngokucophelela ukusatshalaliswa kwamandla nokwakhiwa kweprobe. Lokhu kusungule inkampani njengomholi embonini, inikeza imishini esebenza ngempumelelo emitholampilo yochwepheshe njengoba futhi ijwayelekile ezimakethe ezisafufusa zokunakekelwa kwasekhaya.

Ukuduma okukhulayo kobuchwepheshe be-cold plasma akuzona nje ingozi, ngoba kuletha inhlanganisela emangalisayo yezinzuzo ezibhekana nokulinganiselwa okuningi okutholakala emishinini yobuhle evamile kanye nezinhlelo zokunakekelwa kwesikhumba. Enye yezinzuzo eziphoqa kakhulu yikhono layo lokukhuthaza ukukhula kwamaseli nokuhlelwa kabusha kwe-collagen, okuhumusha ekubeni isikhumba esiqinile, esibushelelezi, futhi esibukeka sisha esikhathini esifushane sokwelashwa. I-cold plasma futhi inezici ezinamandla zokulwa nokuvuvukala kanye nokubulala amagciwane, okuyenza isebenze ngendlela emangalisayo ekwelapheni i-acne ekhuthele, ukulawula i-sebum, nokuvimbela ukusabalala kwezifo esikhumbeni esibuthakathaka. Ngaphezu kwalokho, ucwaningo luye lwabonisa ukuthi ukwelashwa nge-plasma kuthuthukisa ukungena kwemikhiqizo yokunakekela isikhumba ngokwandisa okwesikhashana ukungena kwe-stratum corneum, okusho ukuthi ama-serum akho, ama-peptide, kanye nama-growth factors aya kusebenza kahle kakhulu. Esikhundleni sokuba yithuluzi elisetshenziswa kanye, idivayisi yobuhle ye-plasma isebenza njengeplatifomu enemisebenzi eminingi engabhekana ne-acne, i-pigmentation, imigqa emincane, ama-pores avulekile, i-rosacea, kanye nezinye izinkinga eziningi zobuhle.

Elinye inzuzo ebalulekile ilele ekuvikelekeni okungokwemvelo kwe-cold plasma, esebenza emazingeni okushisa agcina ubuqotho besikhumba sangaphandle kuyilapho isahambisa izimpawu ezijulile zebhayokhemikhali. Lokhu kwenza lobu buchwepheshe bufanele isikhumba esizwelayo, izikhumba ezimnyama, kanye nokunakekelwa kwangemva kwenqubo, lapho ama-laser anolaka noma ama-chemical peels ehlisa ingozi engamukeleki ye-hyperpigmentation noma izibazi. Ngenxa yokuthi akukho sikhathi sokululama, iziguli zingaqhubeka nemisebenzi yazo yansuku zonke ngokushesha ngemva kweseshini, okuyinto eyinhloko yokuthengisa kubasebenzi abamatasa abafuna ukunakekelwa kwesikhumba okucashile kodwa okusebenzayo. Ngaphezu kwalokho, umphumela wemvelo wokubulala amagciwane we-plasma unciphisa ingozi yezifo ezilandelelanayo ngesikhathi sokululama, okuyenza ibe yisengezo esihle sokululama kwangemva kokuhlinzwa kanye nokwelashwa kwesikhumba. Lezi zinzuzo ezihlangene zibeka i-cold plasma njengenye yezindlela eziguquguqukayo futhi ezinomusa eziguli ezitholakalayo embonini yezobuhle namuhla, futhi i-INKUE isebenzise ngayinye yalezi zakhiwo ekwakhiweni kwemishini yayo esezingeni lobungcweti.

Ukuze uthole ngokugcwele amandla edivayisi yobuhle ye-cold plasma, kubalulekile ukuhlola izimiso zesayensi ezilawula ukukhiqizwa kwe-plasma nokusebenzisana kwayo nezicubu zebhayoloji. I-plasma ingakhiqizwa kusetshenziswa izindlela ezimbalwa, kuhlanganise nokukhishwa kwe-dielectric barrier, ukukhishwa kwe-surface microdischarge, namasimu kagesi we-high-frequency, ngayinye ikhiqiza izici zokukhishwa ezihluke kancane kanye namaphrofayili ezinhlobo ezi-active. I-DBD, indlela ethandwa yi-INKUE, inenzuzo ikakhulukazi ngoba idala i-plasma yendawo enkulu, efanayo ekucindezelweni komoya ngaphandle kokudinga igumbi le-vacuum, okwenza kube okusebenzayo kumadivayisi obuhle aphathwayo. Ukukhishwa kukhiqiza ingxube yezinto ezi-active, ikakhulukazi i-reactive oxygen species (ROS) kanye ne-reactive nitrogen species (RNS), okuhlangene kulawula izindlela zokucindezela kwamaseli ngendlela encike kumthamo. Emazingeni angaphakathi kweseli, lezi zinhlobo zisebenza njengama-molecule okusayina akhuphula izindlela zokuzivikela ezi-antioxidant, avule ama-transcription factor, futhi ekugcineni aqalise ukubonakaliswa kwezakhi zofuzo ezihilelekile ekulungiseni nasekuvuseleleni izicubu.

Ubuhle balesi simiso ukuthi umzimba womuntu kakade usebenzisa i-ROS ne-RNS njengama-ejenti emvelo okusayina, ngakho-ke i-cold plasma empeleni iletha inguqulo egxilile kodwa ephephile yesignali amaseli ethu ayibonayo futhi ayiphendulayo ngokwe-physiology. Amazinga aphansi naphakathi naphakathi kwalezi zinhlobo ezisebenzayo akhonjisiwe ukuthi akhuthaza ukwanda kwama-fibroblast, akhulise ukwakheka kwe-collagen, athuthukise ukuhamba kwegazi emithanjeni emincane, futhi akhulise umsebenzi wamaseli omzimba okuzivikela abanomthwalo wokuhlanza nokulungisa amanxeba. Okubalulekile ukuthi izinga lokushisa eliphansi le-plasma liqinisekisa ukuthi isikhumba sangaphandle sihlala sivikelekile ekushiseni, kuvinjwe ukushiswa futhi kuncishiswe ukucindezeleka kwe-oxidative emaselini angaphezulu. Ngokulawula ngokucophelela ukukhishwa kwamandla nokuminyana kwe-plasma, onjiniyela bakwa-INKUE bangakwazi ukwenza izindlela zokwelapha ezihlukene zezimo zesikhumba ezahlukene, kusukela kumaseshini okunakekela anomusa kuya kuma-protocol wokuvuselela anzima kakhulu. Lesi sisekelo sesayensi sichaza ukuthi kungani amadivayisi e-cold plasma eletha imiphumela ebonakalayo futhi ehlala isikhathi eside, nokuthi kungani lobu buchwepheshe bamukelwa odokotela besikhumba abahamba phambili kanye nama-medispa emhlabeni wonke.

Ikusetshenziswa okungokoqobo kobuchwepheshe be-cold plasma kwezobuhle kukhulu ngendlela emangalisayo, okukwenza kube yisengezo esibalulekile kunoma yiluphi uhlu lwezokwelapha lobungcweti. Emaqhuqhuveni nokuvuvukala, i-plasma isebenza njenge-ejenti enamandla elwa namagciwane ebhubhisa amagciwane abangela amaqhuqhuva afana ne-Cutibacterium acnes kuyilapho ithulisa izilonda ezivuvukele futhi isheshisa ukuphola kokuqhuma okusebenzayo. Iyasiza kakhulu emaqhuqhuveni anama-cyst navuvukalayo, lapho izindlela zokwelapha zendabuko zokugcoba zivame ukwehluleka ngenxa yokungangeni kahle noma ukumelana namagciwane. Emkhakheni wokulwa nokuguga, ukugqugquzelwa kwe-collagen ne-elastin okulethwa yi-plasma kubhekana nemigqa emincane, imibimbi, nokuxega ngokwakha kabusha uhlaka lwesakhiwo sesikhumba ngaphakathi, okuholela ekuqineni nokuphakanyisweni okukalekayo ezikhathini ezilandelanayo. Iziguli ezihlanganisa ukwelashwa nge-plasma nezinye izinqubo, njenge-microneedling noma i-LED therapy, zivame ukubika ukuthuthuka okumangalisa kakhulu ngenxa yemiphumela ehlanganyelayo ekwakhiweni kabusha kwezicubu nokumuncwa kwemikhiqizo.

Ngaphezu kwemifiva nemibimbi, imishini ye-cold plasma yenza kahle ekuthuthukiseni ukuthungwa kwesikhumba sonkana ngokulinganisela ukukhiqizwa kwamafutha, ukunciphisa izimbobo zesikhumba ezikhulisiwe, nokulungisa umgoqo wesikhumba owonakele. Lokhu kwenza lobu buchwepheshe bufaneleke kakhulu esikhumbeni esizwelayo nesasisabelayo, kuhlanganise nalabo abahlushwa i-rosacea, i-eczema, noma ubomvu obujwayelekile, izimo ezivame ukungavumeli izindlela zokwelapha ezinzima. Ngaphezu kwalokho, ngenxa yokuthi i-plasma ikhuthaza ukuvuselelwa kwamaseli okusheshayo futhi inemiphumela emnene yokususa isikhumba esingaphezulu, ikhanyisa isikhumba esifiphele futhi inciphise ukubonakala kwamabala amnyama kanye nombala wesikhumba ngokuhamba kwesikhathi. Esimweni sangemva kokuhlinzwa, izici zokulwa nokuvuvukala nezokubulala amagciwane ze-plasma zisekela ukuphola okusheshayo, zinciphisa ukuvuvukala, futhi zinciphise ingozi yezinkinga ngemva kwezinqubo zokuhlinzwa noma ze-laser. Kumakhasimende amaningi abesilisa nabesifazane abamatasa, inhlanganisela yokungabikho kwesikhathi sokuphumula, ukusebenza kabanzi, kanye nemiphumela eqongelelayo yenza i-cold plasma ibe ngesinye sezinto ezikhangayo kakhulu umtholampilo wobuhle wesimanje ongazinikeza.

Yini eyenza amadivayisi obuhle be-cold plasma e-INKUE ahluke kwezinye izinto ezijwayelekile ezimakethe? Ukunaka ngokucophelela umklamo, ukunemba kobunjiniyela, kanye nolwazi lomsebenzisi. Idivayisi ngayinye inedizayini yeprobe enembayo evumela odokotela ukuthi baqondise izindawo ezithile ngokunemba, kungaba belapha ibala elilodwa, indawo ebanzi yobuso, noma isikhumba esibucayi esizungeze amehlo. Amazinga amaningi wamandla afakwe kuyo yonke iyunithi, okunikeza abelaphi ukuguquguquka kokwenza izindlela zokwelapha ezenzelwe umuntu ngamuntu ngokusekelwe ohlotsheni lwesikhumba, ukuzwela, kanye nesimo esithile esilashwayo. Isibonisi sokusebenzisa esilula senza ukusebenza kube lula, okwenza kube lula ngisho nabasebenzi abasanda kuqeqeshwa ukuthi bahlinzeke ngemiphumela engaguquki, yobungcweti. Ngaphandle kokusebenza, i-INKUE igcizelela kakhulu ukuphepha, ihlomisa amadivayisi ayo ngezitifiketi eziqinile kanye namazinga okuhambisana nezidingo zomthetho zamazwe ngamazwe, ukuze imitholampilo nabadayisi bakwazi ukudayisa ngokuzethemba okuphelele.

Ngaphandle kokuphakama kwezobuchwepheshe, amadivayisi e-INKUE aklanyelwe ukonga amandla, aqinise, futhi abize kancane kulo lonke umjikelezo wawo wokusebenza, okunciphisa izindleko zokusebenza emitholampilo futhi kwandise inzuzo yokutshala imali. Iminyaka engamashumi amathathu yesipiliyoni sokukhiqiza kusukela ngo-1992 iye yasiza inkampani ukuthi isungule izinqubo eziqinile zokulawula izinga, eziqinisekisa ukuthi yonke iyunithi ephuma efektri ihlangabezana namazinga aphezulu kakhulu okusebenza nokuthembeka. Ngaphezu kwalokho, i-INKUE inikeza izinsizakalo ezibanzi ze-OEM ne-ODM, ezivumela izinhlobo zomkhiqizo ukuthi zenze ngokwezifiso konke kusukela ekubukekeni kwedivayisi nokuphawulwa komkhiqizo kuya kumapharamitha athile okusebenza, iqinisekisa ukuthi umkhiqizo wokugcina uhambisana ngokuphelele nokuma kwawo emakethe kanye nokulindelwe amakhasimende. Noma ngabe uyi-startup efuna ukwethula idivayisi yakho yokuqala ye-plasma noma uphawu olusunguliwe olukhulisa iphothifoliyo yakho, inhlanganisela ye-INKUE yokusungula, ukwenza ngokwezifiso, nokusekelwa kuyenza ibe umlingani okhiqizayo ofanelekile. Lokhu kuzinikela okujulile ezingeni lokulunga nasekubambisaneni yingakho i-INKUE isiphenduke igama elithembekile phakathi kwabaholi embonini yezobuhle emhlabeni wonke.

Ukukhulisa imiphumela yedivayisi yobuhle ye-cold plasma kudinga indlela ecatshangelwayo eqala kude ngaphambi kokuba iprobe ithinte isikhumba. Ukulungiselela ngaphambi kokwelashwa kufanele kuqale ngokuhlanza ubuso ngokuphelele ukususa imakeyiphu, amafutha, nokungcola okungaphazamisa ukukhishwa kwe-plasma, kulandele ukuhlola kahle isimo sesikhumba sekhasimende nezinga lokuzwela. Ukuze uthole imiphumela engcono kakhulu, isikhumba kufanele somile ngokuphelele, ngoba umswakama ungashintsha ukuhamba kukagesi futhi kunciphise ukufana kokwelashwa. Ngesikhathi seshini, udokotela ukhetha imodi yamandla efanele ngokusekelwe ekubekezeleleni kwekhasimende kanye nenjongo yokwelashwa, bese ehambisa iprobe ngokulinganayo endaweni okuhlosiwe ngemivimbo ehamba kancane, edlulanayo ukuqinisekisa ukuchayeka kwe-plasma okungaguquki. Ishini elilodwa ngokuvamile lithatha imizuzu engu-15 kuya ku-30 kuye ngobukhulu bendawo eyelashwayo, futhi amakhasimende angase azwe ukufudumala okuncane noma ukugwinya okuncane okuvame ukubekezelelwa kahle.

Ukunakekelwa kwangemva kokwelashwa nakho kubaluleke ngokulinganayo futhi kuhilela ukusebenzisa imaskhi ethambisayo noma i-serum efaka umswakama ukuze kuthulise isikhumba futhi kuthuthukise ukusabela kokuvuselela okuqalwe yi-plasma. Amaklayenti kufanele elulekwe ukuthi agweme ukukhanya kwelanga okuqondile, ukuxebuka kwesikhumba okunamandla, kanye nemikhiqizo yamakhemikhali eqinile okungenani amahora angu-24 kuya kwangu-48 ngemva kweseshini ukuze kuvikelwe isikhumba esisanda kuvuselelwa. Ngenxa yokuthi i-plasma yandisa ukungena komkhiqizo, lesi yisikhathi esikahle sokusebenzisa ama-growth factors, ama-peptides, kanye nama-antioxidants, okuzomuncwa ngempumelelo enkulu kunanoma yisiphi esinye isikhathi ohlelweni lokunakekela isikhumba. Ezigulini ezinamabhamuza, udokotela angase ancome uchungechunge lwamaseshini amabili kuya kwamathathu ahlukaniswe ngeviki elilodwa kuya kwamabili ukuze kulawulwe ukuqhuma okusebenzayo, kuyilapho amaklayenti okulwa nokuguga evame ukuqaphela imiphumela engcono kakhulu ngamaseshini okugcina okwenziwa nyanga zonke. Ngokulandela lezi zinqubo ngokuzimisela, imitholampilo inganikeza imiphumela engaguquki, ephindaphindekayo egcina amaklayenti ebuya futhi yakhe idumela eliqinile lokwelashwa nge-plasma emakethe yawo yasendaweni.

Ikhono lamadivayisi e-cold plasma lisekelwa ucwaningo lwezempilo olukhulayo oluqinisekisa ukusetshenziswa kwawo ezinhlobonhlobo zezimo zesikhumba. Ucwaningo olwenziwe mayelana nokuvuselelwa kwesikhumba nge-plasma lubonise ukuthuthuka okukhulu esikhumbeni esifiphele, ukujula kwemibimbi, izibazi zomqubuko, nokuxega kobuso ngemuva kochungechunge lokwelashwa, kanti iziguli nodokotela abahlolayo bobabili babika izinguquko ezibonakalayo ekuqineni nasekuqiniseni. Ezinhlolweni eziningi, izilinganiso eziqondile ezifana nokugqwala kwesikhumba, ukulahleka kwamanzi esikhumbeni, nokuminyana kwe-collagen zibonise ukuthuthuka okubalulekile ngokwezibalo ngemuva nje kwezikhathi ezine kuya kweziyisithupha, okuqinisekisa umsebenzi webhayoloji we-plasma ezingeni lamaseli. Indlela echazwe ngaphambili, okuwukusebenza kwezindlela zokudlulisa umyalezo ze-ROS/RNS, ixhunyaniswe ngqo nokwanda kokufakwa kwe-collagen kanye nokuthuthukiswa kokuhlelwa kabusha kwe-extracellular matrix kuma-biopsies esikhumba somuntu. Lokhu okutholakele kunikeza isiqinisekiso esiqinile kochwepheshe abacabangela ukwengeza i-cold plasma ohlwini lwabo lwezinsizakalo kanye nabasebenzisi abangase bangabaze ngenye into "eyisimangaliso" yokulwa nokuguga.

Imiphumela yangempela, nokho, incike kakhulu ekhwalithini yemishini kanye nekhono lomsebenzisi, yingakho ukukhetha idivayisi kubaluleke kangaka kulo mkhakha. Ama-probe e-INKUE enziwe ngobuchwepheshe obunembayo kanye nokukhipha amandla okungaguquguquki kuqinisekisa ukuthi imiphumela yomtholampilo etholakala ezifundweni ingaphindwa ngokuthembekile emsebenzini wansuku zonke, kuqede ukungafani okuhlupha amadivayisi asezingeni eliphansi. Amaklayenti ngokuvamile angabona ukuncipha kosayizi wembobo kanye nokuthuthuka okusheshayo kokukhanya kwesikhumba ngemuva kweseshini yokuqala, kanti izinguquko ezijulile ekujuleni kwemibimbi nokuqina zivela emasontweni alandelayo njengoba ukwakheka kwe-collagen kuqhubeka. Kulabo abanenkinga yamabhamu, ukuncipha okuphawulekayo kwezilonda ezisebenzayo nokuvuvukala kuvame ukubikwa phakathi nezinsuku, kanye nokuncipha kwe-post-inflammatory hyperpigmentation ngokuhamba kwesikhathi. Ngokubeka okulindelekile okungokoqobo nokunikeza izinhlelo zokwelashwa ezifanele, i-INKUE yenza abalingani bayo bakwazi ukuthola amazinga aphezulu okwaneliseka kwamaklayenti nokwethembeka kwesikhathi eside, okuyizinto eziqhuba ukukhula kwebhizinisi emakethe yezobuhle enokuncintisana.

Ukukhetha umkhiqizi ofanele kungaba yisinqumo esibaluleke kakhulu kunoma yimuphi umkhiqizo ongena emakethe yamadivayisi obuhle be-cold plasma, futhi i-INKUE inikeza inhlanganisela ekhangayo yobuchwepheshe, ingqalasizinda, kanye nesevisi okumbalwa abancintisani abangayifinyelela. Ithimba layo locwaningo nentuthuko elichwepheshile lihlala lihlola ubuchwepheshe obusha be-plasma kanye nezindlela zokwelapha, liqinisekisa ukuthi amadivayisi ayo ahlala ngaphambi kwamathrendi emboni kanye nokulindelwe abathengi. Izinyathelo zokulawula ikhwalithi eziqinile ziyasetshenziswa kuzo zonke izigaba zokukhiqiza, kusukela ekutholeni izingxenye kuze kufike ekuhlanganiseni kokugcina, okuqinisekisa ukuthi idivayisi ngayinye ithembekile, iphephile, futhi ihlala ifana ekusebenzeni. I-INKUE inezitifiketi ezifanele kanye nezimvume zokuhambisana, okuhlanganisa i-CE, i-FDA, kanye namanye amazinga omhlaba, okwenza kube lula ukugunyazwa kokulawula kwabasabalalisi kanye nemitholampilo ezimakethe zomhlaba. Le ndlela egxile ekuhambisaneni inciphisa umthwalo kubalingani futhi isheshisa isikhathi sokufika emakethe kwemikhiqizo emisha, inzuzo enkulu yokuncintisana embonini lapho ukuba ngowokuqala kuvame ukunquma isabelo semakethe.

Ngaphandle kokukhiqiza okusezingeni eliphezulu, i-INKUE ihlinzeka ngosekelo oluphelele lwangemuva kokuthengisa, okuhlanganisa izinhlelo zokuqeqesha abasebenzi, izinto zokumaketha, nosizo lwezobuchwepheshe olusabelayo, okuqinisekisa ukuthi abalingani bangakwazi ukuqala futhi bandise ukunikezwa kwabo ngamadivayisi e-plasma ngokuzethemba. Inkampani futhi yamukela ukusebenzisana kwe-OEM/ODM, inikeza izinketho zokwenza ngokwezifiso eziguquguqukayo ezihlanganisa uphawu, ukubukeka, umsebenzi, nokupakisha, njengoba kuchaziwe ku-Ikhasi Elisha1 okubonisa amandla okukhiqiza nezixazululo eziqondene namabhrendi omhlaba. Kulabo abafuna ukuqonda ifa lenkampani namakhono ayo, i- Mayelana Nathi ikhasi lilandisa ifa lokusungula kanye nokubambisana komhlaba okuthatha iminyaka engaphezu kwamashumi amathathu. Noma ngabe uthuthukisa isistimu yekilini esezingeni eliphezulu noma idivayisi yasekhaya efinyelelekayo, irekhodi eliqinisekisiwe le-INKUE, ukujula kobunjiniyela, nokuzibophezela ekubambisaneni kuyenza ibe ngumlingani ofanelekile wokukhula kwebhizinisi. Ukuze uhlole uhla oluphelele lokunikezwayo namakhono efektri, amaklayenti angaba ngamakhasimende ayakhuthazwa ukuthi avakashele i- Ikhaya ikhasi futhi uthole ukuthi kungani i-INKUE ibonwa njengomkhiqizi ohamba phambili wamadivayisi obuhle kusukela ngo-1992.

Ukunakekelwa kahle kwedivayisi yakho yobuhle ye-cold plasma kubalulekile hhayi kuphela ukuphepha kodwa futhi ukuqinisekisa imiphumela yokwelashwa engaguquki kanye nokwandisa isikhathi sokuphila kokutshalomali kwakho. Ngemuva kokusetshenziswa ngakunye, iprobe ne-handpiece kufanele zisulwe ngendwangu ethambile, eyomile noma isibulala-magciwane esithambile esinconywa umkhiqizi, kuqinisekiswe ukuthi akukho nsalela noma into ephilayo enqwabelanayo ebusweni be-electrode. Gcina idivayisi endaweni ehlanzekile, eyomile kude nelanga eliqondile, amazinga okushisa adlulele, nomswakama ophezulu, okungase konakalise izingxenye ze-elekthronikhi futhi kulimaze ukusebenza ngokuhamba kwesikhathi. Iprobe iyingxenye esetshenziswayo ezoguga ngokwemvelo ngokusetshenziswa, futhi kufanele ihlolwe njalo ukuthola izimpawu zomonakalo noma izinga lokukhishwa elincishisiwe, kanti ukushintshwa kufanele kutholakale ngqo kwa-INKUE ukuze kugcinwe izicaciso ezifanele. Ukulinganisa njalo, lapho kutholakala khona, kuyanconywa futhi ukugcina ukukhishwa kwamandla kungaphakathi kwesikhathi sokwelapha nokugwema ukwelashwa ngaphansi noma ngaphezulu kwamaklayenti.

Izinyathelo zokuphepha akufanele zishaywe indiva, ngisho noma amadivayisi e-cold plasma emvelo yawo emnene. Abasebenzi kufanele balandele imihlahlandlela yomkhiqizi mayelana nokungavunyelwa kokwelashwa, okuhlanganisa ukukhulelwa, izifo zesikhumba ezisebenzayo, ama-pacemaker, kanye nemithi ethile yokwenza ukukhanya kube nomthelela, futhi njalo benze ukuhlolwa kwesikhumba kubathengi abasha. Idivayisi kufanele igcinwe kude namanzi futhi isetshenziswe kuphela esikhumbeni esiphelele nesinempilo, hhayi phezu kwamanxeba avulekile, ama-mole, noma izilonda ezisolisayo ngaphandle uma kuqondiswa udokotela. Uma iklayenti lizwa ukungaphatheki kahle okungajwayelekile, ukubomvu ngokweqile, noma amabhamuza, iseshini kufanele imiswe ngokushesha futhi kusetshenziswe ukunakekelwa okufanele kwangemuva, njenganoma yiluphi inqubo yobuhle. Ukuxazulula izinkinga ezijwayelekile, njengokukhishwa okubuthakathaka, ukugqabhuka kwezikhathi ezithile, noma imilayezo yephutha, ngokuvamile kulula ngosizo lwethimba lobuchwepheshe le-INKUE, elitholakalayo ukusiza ozakwethu ngokushesha nangempumelelo. Ngokufaka lezi zinqubo zokunakekela nokuphepha ekusebenzeni kwansuku zonke komtholampilo, uvikelela kokubili amaklayenti akho nedumela lakho lebhizinisi kuyilapho wandisa inani ledivayisi yakho ye-plasma.

Idivayisi yobuhle ye-plasma ebandayo iyithuluzi le-elekthronikhi elikhiqiza ukukhishwa kwegesi elishisayo elinezinga lokushisa eliphansi, noma i-plasma, ekugcineni kweprobe futhi liyise esikhumbeni. Le plasma iletha izinhlobo ze-oksijini ne-nitrogen ezisebenzayo ezivusa izindlela zokulungisa amaseli, zikhuthaze ukukhiqizwa kwe-collagen, futhi zibulale amagciwane, konke ngaphandle kokushisa noma ukulimaza i-epidermis. Amadivayisi e-INKUE asebenzisa ubuchwepheshe obuthuthukisiwe be-dielectric barrier discharge (DBD) ukukhiqiza indawo ye-plasma ezinzile, efanayo ephephile futhi esebenzayo ezinhlobonhlobo zezinkinga zesikhumba.

Cha, ukwelashwa nge-cold plasma ngokuvamile kukhululekile futhi kubekezelelwa kahle yiziguli eziningi, kukhiqiza kuphela umuzwa wokufudumala okuncane noma wokugwinya esikhumbeni. Ngenxa yokuthi i-plasma isebenza ezingeni lokushisa eliphansi, ayibangeli ukushisa, ukugwinya, noma ubuhlungu obukhali obuhambisana nama-laser noma amadivayisi e-radiofrequency. Lokhu kuyenza ibe yinketho enhle kakhulu kubantu abazwelayo kanye nalabo abakhathazekile ngokungakhululeki, futhi amaklayenti amaningi achaza lokhu okuhlangenwe nakho njengokukhululekile futhi okumnandi.

Amaklayenti amaningi aqaphela ukuthuthuka okusheshayo ekukhanyeni kwesikhumba, ukubushelela, nosayizi wembobo ngemuva kweseshini yawo yokuqala ngenxa yemiphumela emnene yokukhuphula nokuqinisa ye-plasma. Izinguquko ezibaluleke kakhulu, njengokuncipha kokujula kwemibimbi, ukuqina okuthuthukisiwe, nokuncipha kwezibazi zomqubuko, ngokuvamile zivela phakathi namasonto ambalwa njengoba ukulungiswa kwe-collagen kuqhubeka. Isikhathi esigcwele sokwelashwa ngokuvamile sinconywa ukuze kuzuzwe imiphumela engcono kakhulu nehlala isikhathi eside, nemiphumela ibonakala phakathi namasonto ama-3 kuye kwayi-6 kuye ngesimo eselashwayo.

Inani lezikhathi ezidingekayo liyahluka kumuntu ngamuntu kanye nesimo eselashwayo, kodwa izinqubo eziningi zomtholampilo zincoma uchungechunge lwezikhathi ezi-4 kuya kwezi-8 ezihlukaniswe ngezikhathi ezingu-1 kuya kwezi-2 zamaviki ukuze kwelashwe amabhamuza kanye nezinjongo zokulwa nokuguga. Izikhathi zokunakekela kanye ngenyanga ziyanconywa ukuze kugcinwe imiphumela futhi kuqhubeke ukukhuthaza ukukhiqizwa kwe-collagen ngokuhamba kwesikhathi. Amazinga amandla alungisekayo edivayisi yakho ye-INKUE avumela odokotela ukuthi benze uhlelo lokwelashwa oluhambisana nohlobo lwesikhumba sekhasimende kanye nomphumela ofunwayo.

Ukunakekelwa kwangemuva kokwelashwa kuhlanganisa ukusebenzisa imaski noma i-serum ethambisa futhi enomswakama ukuze kuthulise isikhumba futhi kukhulise impendulo yokuvuselela eqalwe yi-plasma. Amaklayenti kufanele agweme ukukhanya kwelanga okuqondile, izinto zokuxubha ezinamandla, nemikhiqizo yamakhemikhali enamandla okungenani amahora angu-24 kuya kwangu-48, futhi i-sunscreen iyisidingo phakathi nesonto elilandelayo. Ngenxa yokuthi i-plasma yandisa ukungena komkhiqizo, lesi yisikhathi esihle kakhulu sokusebenzisa ama-growth factors, ama-peptides, nama-antioxidants ukuze kwandiswe imiphumela yokulwa nokuguga yokwelashwa.

Yebo, i-cold plasma iphumelela kakhulu ekwelapheni izinduna ngenxa yezakhiwo zayo ezinamandla zokubulala amagciwane nokulwa nokuvuvukala, okunciphisa ukuqhuma okusebenzayo futhi kukhuthaze ukuphola ngokushesha ngaphandle kokulimaza umgoqo wesikhumba. Futhi ilungele izinhlobo zesikhumba ezizwelayo nezisabelayo, kuhlanganise nalezo ezine-rosacea noma ubomvu obungapheli, ngoba ukukhishwa kwamandla okushisa okuphansi kumnene futhi akucasuli. Lokhu kuguquguquka kwenza amadivayisi obuhle be-plasma abe yisinqumo esithandwayo kumakhasimende angakwazi ukubekezelela ukwelashwa kwezinduna kwendabuko noma izinqubo ezinzima zokulwa nokuguga.

Amathuluzi e-cold plasma anezinzuzo ezimbalwa uma kuqhathaniswa namalaser, okuhlanganisa ukungabikho kwesikhathi sokuphumula, ukungabikho kokulimala okushisayo, ukufaneleka kuzo zonke izinhlobo zesikhumba, kanye nengozi encane yezinkinga zombala noma izibazi. Lobu buchwepheshe futhi bunikeza izinzuzo ezimbili: ukuvuselelwa kwesikhumba kanye nokuvinjelwa kwamagciwane, okubenza babe usizo kuzo zombili izinjongo zobuhle nezokwelapha. Ngaphezu kwalokho, amathuluzi e-plasma avame ukuba mancane, ongawonga amandla, futhi angabizi kakhulu kunezinto ezifanayo zamalaser, okubenza babe yindlela efinyelelekayo yemitholampilo eminingi kanye nabasebenzisi basekhaya.

I-INKUE iletha isipiliyoni sokukhiqiza esingaphezu kwamashumi amathathu eminyaka kusukela ngo-1992, ithimba lochwepheshe lokucwaninga nokuthuthukisa, ukulawulwa kwekhwalithi okuqinile, kanye nezitifiketi zamazwe ngamazwe kuyo yonke imikhiqizo eyilethayo. Inkampani inikeza ukwenza ngokwezifiso okuphelele kwe-OEM/ODM, okuvumela izinhlobo ukuthi zilungiselele amadivayisi ngokuhambisana nokuma kwawo kwemakethe ngqo, kanye nokusekelwa okunamandla kwangemva kokuthengisa, ukuqeqeshwa, kanye nosizo lobuchwepheshe. Le nhlanganisela yobungcweti bobunjiniyela kanye nesevisi egxile ebambisanweni yenza i-INKUE ibe yisinqumo esithembekile sokwethula imigqa yamadivayisi e-cold plasma ephumelelayo, njengoba kuchaziwe kuyi-Izindaba ikhasi nezinye izinsiza.

Ukunakekelwa kwansuku zonke okulula kuhlanganisa ukusula iprobe ne-handpiece ngendwangu ethambile, eyomile ngemuva kokusetshenziswa ngakunye nokugcina idivayisi endaweni ehlanzekile, eyomile kude nomswakama namazinga okushisa adlulele. Iprobe kufanele ihlolwe ngezikhathi ezithile ukuze kubonakale ukuguga futhi ishintshwe ngezingxenye zangempela ze-INKUE uma kudingeka ukuze kugcinwe ukusebenza okuphezulu. Ukulandela imihlahlandlela yokunakekelwa yomkhiqizi nokusekelwa kokuxazulula izinkinga kuqinisekisa ukuthi idivayisi yakho ihlala iphephile futhi iletha imiphumela engaguquki iminyaka ezayo.

Impela, i-INKUE yamukela ukusebenzisana kwe-OEM/ODM futhi inikeza izinsizakalo zokwenza ngokwezifiso ezibanzi ezihlanganisa uphawu, ukubukeka, umsebenzi, nokupakisha ukuze kuhlangatshezwane nezidingo ezithile zebhizinisi lakho. Ithimba elizinikele lenkampani lisebenza eduze nabalingani ukuthuthukisa imikhiqizo eyenzelwe ukuhlangabezana nezidingo zemakethe nokulindelwe abathengi. Ukuze ufunde kabanzi mayelana nenqubo yokwenza ngokwezifiso namakhono okukhiqiza, abalingani abangaba khona bangahlola i-Ikhasi Elisha isisetshenziswa noma baxhumane ngqo ne-INKUE ukuze bathole ukubonisana.